Alexandre Lacazette has been ruled out for four to six weeks after undergoing a minor procedure on his knee.
Arsenal said on Tuesday that Lacazette “had an arthroscopy on his left knee in London” and that he “will now undergo a period of rehabilitation.”
Alexandre Lacazette had been expected to start in both legs of the round-of-32 Europa League tie against Ostersund.
Lacazette has lost his Premier League starting place to new signing Pierre-Emerick Aubameyang, but the former Borussia Dortmund forward is cup tied in the Europa League.
Arsenal play at the Swedish side on Thursday with the return leg at the Emirates a week later.